Scientific & Regulatory Resources

Resources for scientific and regulatory information and updates:

2025: Herbal Products for Depression in Type 2 Diabetes Mellitus Patients: A Systematic Review and Meta-Analysis

For patients with T2DM and depression, herbal products were more effective than placebo in relieving depression symptoms. Additionally, herbal products combined with SSRIs alleviated depression and blood glucose levels more effectively than SSRIs alone. To verify the clinical efficacy of herbal products, high-quality studies are warranted.” – Yang et al., 2025

Yang, R., Wu, Y., Zhang, L., Wu, L., Qin, L., & Liu, T. (2025). Herbal Products for Depression in Type 2 Diabetes Mellitus Patients: A Systematic Review and Meta-Analysis. Phytotherapy research : PTR, 10.1002/ptr.8505. Advance online publication. https://doi.org/10.1002/ptr.8505

Herbal Products for Depression in Type 2 Diabetes Mellitus Patients: A Systematic Review and Meta-Analysis – PubMed

2025: Nutritional and herbal interventions for polycystic ovary syndrome (PCOS): a comprehensive review of dietary approaches, macronutrient impact, and herbal medicine in management – Muhammed Saeed et al., 2025

“..cinnamon, curcumin, sage, fennel, and traditional Chinese herbal medicine are among some of the herbal remedies that so far show good potential to be the perfect complementary therapy tools as they create better glycemic control, inflammation reduction, and menstrual cycle regularization. Even though the findings are promising, the current supply of clinical trials for standardizing these nutritional and herbal protocols is lacking. Overall, this report stresses the fact that a customized, holistic diet regime is the best treatment for women with PCOS to make them feel well and live a long and healthy life.” – Muhammed Saeed et al., 2025

Muhammed Saeed, A. A., Noreen, S., Awlqadr, F. H., Farooq, M. I., Qadeer, M., Rai, N., Farag, H. A., & Saeed, M. N. (2025). Nutritional and herbal interventions for polycystic ovary syndrome (PCOS): a comprehensive review of dietary approaches, macronutrient impact, and herbal medicine in management. Journal of health, population, and nutrition44(1), 143. https://doi.org/10.1186/s41043-025-00899-y

Nutritional and herbal interventions for polycystic ovary syndrome (PCOS): a comprehensive review of dietary approaches, macronutrient impact, and herbal medicine in management – PubMed

2024: Sustainable Herbs Program: American Botanical Council

Home – Sustainable Herbs Program; Sustainable Herbs Program ToolKit V.2: Sustainable Herbs Program ToolKit V.2 – Sustainable Herbs Program

2024: Traditional, Complementary and Integrative Medicine, World Health Organization (WHO)

Traditional, Complementary and Integrative Medicine (who.int)

2024: Herbs at a Glance, National Center for Complementary and Integrative Health, NIH

Herbs at a Glance | NCCIH (nih.gov)

2023: Government of Canada, Natural Health Products (Modified:  2023-12-15)

Natural health products – Canada.ca

2023: Government of Canada, Natural Health Products Ingredients Database (Modified: 2023-03-15)

Natural Health Products Ingredients Database – Canada.ca (hc-sc.gc.ca)

2023: Natural health product licence application form user guide, Government of Canada

Natural health product licence application form user guide – Natural health product licence application form user guide – Canada.ca (hc-sc.gc.ca)

2023: WHO international standard terminologies on ayurveda, World Health Organization (10 January 2023)

WHO international standard terminologies on ayurveda

2023: Medicinal Mushrooms (PDQ®)–Patient Version – National Cancer Institute (NCI)

Mushrooms – NCI (cancer.gov)

2022: Narratives of Herbal Medicine Utilisation in the United Kingdom: Scoping Literature Review, Longden-Naufal, Rolfe. & Mackonochie

Longden-Naufal C, Rolfe V, Mackonochie M. Narratives of Herbal Medicine Utilisation in the United Kingdom: Scoping Literature Review. Front Pharmacol. 2022;13:886574. Published 2022 Aug 25. doi:10.3389/fphar.2022.886574

2019: WHO global report on traditional and complementary medicine

World Health Organization. (‎2019)‎. WHO global report on traditional and complementary medicine 2019. World Health Organization. https://iris.who.int/handle/10665/312342.

2019: Licensed Natural Health Products Database (LNHPD), Government of Canada

Licensed Natural Health Products Database (LNHPD) – Canada.ca

2019: The importance of herbal medicine use in the German health-care system: prevalence, usage pattern, and influencing factors

Welz, A.N., Emberger-Klein, A. & Menrad, K. The importance of herbal medicine use in the German health-care system: prevalence, usage pattern, and influencing factors. BMC Health Serv Res 19, 952 (2019). https://doi.org/10.1186/s12913-019-4739-0